Title
Health outcomes and experiences of direct-to-consumer high-intensity screening using both whole-body magnetic resonance imaging and cardiological examination
Author
Hommes, D.
Klatte, D.
Otten, W.
Beltman, M.
Klass, G.
Zand, A.
Sprangers, R.
Publication year
2020
Abstract
Background. Alongside a clinical and research setting, whole body magnetic resonance imaging (WB-MRI) is increasingly offered as a direct-to-consumer screening service. Data is needed on the clinical relevance of findings and associated psychological impact of such screening. Therefore, we conducted a prospective follow-up study to provide insight in the effectiveness and psychological impact of direct-to-consumer screening using both WB-MRI and cardiological examination. Methods and findings. The study population consisted of 3603 voluntary, primarily middle-aged participants who underwent commercial WB-MRI and cardiological screening at one of 6 study clinics in Germany or the Netherlands between July 2014 and March 2016. MRI investigation consisted of directed scans of the brain, neck, abdomen and pelvis. Cardiovascular examination included pulmonary function, resting electrocardiogram, transthoracic echocardiogram and a bicycle exercise stress test. Findings were assessed by experienced radiologists and cardiologists. In addition, participants were inquired about several (psychological) domains, including the expectations and consequences of the screening procedure. Out of 3603 individuals, 402 (11.2%) demonstrated abnormal MRI (n = 381) and/or cardiological findings (n = 79) for which they were advised to undergo further consultation
Subject
Health
Healthcare
Body magnetic resonance imaging
Cardiology
Examination
Screening
MRI
Consumer
Work and Employment
Healthy Living
To reference this document use:
http://resolver.tudelft.nl/uuid:715a66ef-8161-4052-96c9-0754304e8050
DOI
https://doi.org/10.1371/journal.pone.0242066
TNO identifier
884065
Source
Plos One, 15 (15), e0242066
Document type
article