Title
Radioimmunoassay for pancreatic glucagon based on specific derivatisation of the hormone
Author
Nooijen, W.J.
Koppert, P.W.
Gaubius instituut TNO
Publication year
1981
Abstract
A specific glucagon antiserum was generated in rabbits using a derivatisation of the methionine residue in glucagon. A sensitive and specific assay for glucagon has been developed. Interference with the assay system by plasma factors was abolished by both extraction of plasma samples and the production of glucagon-free plasma for each individual. Chemicals/CAS: glucagon, 11140-85-5, 62340-29-8, 9007-92-5; Aprotinin, 9087-70-1; Arginine, 74-79-3; Glucagon, 9007-92-5; S-methylglucagon, 68600-12-4
Subject
Biology
Adult
Animal
Aprotinin
Arginine
Drug Stability
Fasting
Glucagon
Glucose Tolerance Test
Human
Middle Age
Pancreas
Rabbits
Radioimmunoassay
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TNO identifier
229083
ISSN
0004-5632
Source
Annals of Clinical Biochemistry, 18 (2), 118-122
Document type
article