Print Email Facebook Twitter Prevalence and independent risk factors for hearing loss in NICU infants Title Prevalence and independent risk factors for hearing loss in NICU infants Author Hille, E.T.M. van Straaten, H.L.M. Verkerk, P.H. van Straaten, I. Verkerk, P. Hille, E. Baerts, W. Bunkers, C. Smink, E. van Elburg, R. de Kleine, M. Kok, J.H. Ilsen, A. Visser, D. Steiner, K. de Vries, L.S. Weisglas-Kuperus, N. Sprij, A. Lopriori, E. Brokx, J. Gavilanes, D. Geven, W. Bos, A. TNO Kwaliteit van Leven Publication year 2007 Abstract Aim: To determine the prevalence and independent relationship between hearing loss and risk factors in a representative neonatal intensive care unit (NICU) population. Methods: Automated auditory brainstem response (AABR) hearing screening has been introduced since 1998 in the Dutch NICUs. After a second AABR failure, diagnostic ABR was used to establish diagnosis of hearing loss. Newborns who died before the age of 3 months were excluded. In the present study only the NICU infants who were born with a gestational age <30 weeks and/or a birth weight <1000 g between October 1, 1998 and January 1, 2002 were included. Risk factors included in the study were familial hearing loss, in utero infections, craniofacial anomalies, birth weight <1500g, hyperbilirubinemia, ototoxic medications, cerebral complications, severe birth asphyxia, assisted ventilation ≥5 days and syndromes. Results: A nationwide cohort of 2186 newborns were included. Mean gestational age was 28.5 weeks (SD 1.6) and mean birth weight was 1039 g (SD 256). Prevalence of uni- or bilateral hearing loss was 3.2% (71/2186; 95% CI 2.6-4.1). Multivariate analysis revealed that the only independent risk factors for hearing loss were severe birth asphyxia (OR 1.7; 95% CI 1.0-2.7) and assisted ventilation ≥5 days (OR 3.6; 95% CI 2.1-6.0). Conclusion: The prevalence of hearing loss in a representative NICU population was 3.2%. Independent risk factors for hearing loss were severe birth asphyxia and assisted ventilation ≥5 days. © 2007 The Author(s). Subject HealthHearing screeningNICU populationRisk factorsAssisted ventilationBirth weightCraniofacial malformationDisease severityFamilial diseaseHyperbilirubinemiaIntrauterine infectionMajor clinical studyNewbornNewborn intensive careOtotoxicityPerinatal asphyxiaPrevalenceSyndromeAsphyxia NeonatorumEvoked Potentials, Auditory, Brain StemGestational AgeHearing LossHumansInfant, NewbornInfant, PrematureInfant, Very Low Birth WeightIntensive Care Units, NeonatalNeonatal ScreeningNetherlandsRespiration, ArtificialTime Factors To reference this document use: http://resolver.tudelft.nl/uuid:6876a540-a206-491d-bb2f-53bb72f9eacf DOI https://doi.org/10.1111/j.1651-2227.2007.00398.x TNO identifier 240101 ISSN 0803-5253 Source Acta Paediatrica, International Journal of Paediatrics, 96 (8), 1155-1158 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.