Print Email Facebook Twitter Bidirectional associations between alcohol consumption and health-related quality of life amongst young and middle-aged women Title Bidirectional associations between alcohol consumption and health-related quality of life amongst young and middle-aged women Author Schrieks, I.C. Wei, M.Y. Rimm, E.B. Okereke, O.I. Kawachi, I. Hendriks, H.F.J. Mukamal, K.J. Publication year 2016 Abstract Background: Evidence from cross-sectional studies has suggested a positive association between moderate alcohol consumption and health-related quality of life but prospective data remain scarce. Objectives: To examine the bidirectional relationships between alcohol consumption and health-related quality of life using a longitudinal study design. Methods: A total of 92 448 participants of the Nurses' Health Study II reported their alcohol consumption (in 1991, 1995, 1999 and 2003) and health-related quality of life (in 1993, 1997 and 2001). Using generalized estimating equations, we modelled the physical and mental component summary (PCS and MCS) scores as a function of alcohol consumption 2 years earlier (n = 88 363) and vice versa (n = 84 621). Results: Greater alcohol consumption was associated with better PCS scores 2 years later in a dose-response manner up to ~1 serving daily [mean difference (β) = 0.67 ± 0.06 PCS units, for moderate versus infrequent drinkers]. After adjustment for previous PCS, a similar but attenuated pattern was observed (β = 0.33 ± 0.07). Moderate alcohol consumption was not related to MCS, whereas moderate-to-heavy alcohol consumption was associated with lower MCS scores (β = -0.34 ± 0.15). Higher PCS scores were associated with greater alcohol consumption 2 years later, also after adjustment for previous alcohol consumption (β = 0.53 ± 0.05 g day-1). MCS was not associated with alcohol consumption 2 years later. Conclusion: Amongst young and middle-aged women, moderate alcohol intake was associated with a small improvement in physical health-related quality of life 2 years later and vice versa. Moderate alcohol consumption was not associated with mental health-related quality of life in either direction. © 2016 The Association for the Publication of the Journal of Internal Medicine. Subject LifeMSB - Microbiology and Systems BiologyELSS - Earth, Life and Social SciencesFood and NutritionBiologyHealthy LivingAlcohol drinkingAlcoholic beveragesFemalesHealthLongitudinal studiesQuality of life To reference this document use: http://resolver.tudelft.nl/uuid:65182753-d809-4723-b641-600b9175f87b DOI https://doi.org/10.1111/joim.12453 TNO identifier 534101 ISSN 0954-6820 Source Journal of Internal Medicine, 279 (4), 376-387 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.