Title
Ca binding of rat fibrinogen and fibrin(ogen) degradation products
Author
van Ruijven-Vermeer, I.A.M.
Nieuwenhuizen, W.
Nooijen, W.J.
Gaubius instituut TNO
Publication year
1978
Abstract
The authors studied the binding of Ca to rat fibrinogen and plasmic fibrin(ogen) degradation products by means of equilibrium dialysis with special reference to the protective effect of Ca2+ in the plasmic degradation of fibrinogen. Direct binding studies demonstrate that rat fibrinogen and the plasmic degradation products D(cate) and D-dimer strongly bind Ca2+ and that this binding in D(cate) and D-dimer is correlated with a protective effect against further plasmic degradation. Chemicals/CAS: calcium, 7440-70-2; fibrinogen, 9001-32-5; Calcium, 7440-70-2; Egtazic Acid, 67-42-5; Fibrin Fibrinogen Degradation Products; Fibrinogen, 9001-32-5
Subject
Animal experiment
In vitro study
Animal
Binding Sites
Calcium
Egtazic Acid
Fibrin Fibrinogen Degradation Products
Fibrinogen
Kinetics
Protein Binding
Rats
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DOI
https://doi.org/10.1016/0014-5793(78)80831-x
TNO identifier
228416
ISSN
0014-5793
Source
FEBS Letters, 93 (1), 177-180
Document type
article