Glucagon receptors: Are they present on human blood cells?
van Hinsbergh, V.W.M.
Gaubius instituut TNO
Binding of glucagon to and its degradation by human mononuclear leukocytes and erythrocytes was investigated. Labeled glucagon binds to these cells, but can be displaced only by unlabeled glucagon at pharmacologically high concentrations. It is concluded that glucagon binding to human blood cells does not represent receptors of physiological importance and is of no value to the determination of glucagon sensitivity in man. Chemicals/CAS: Glucagon, 9007-92-5; Receptors, Cell Surface; Receptors, Glucagon
To reference this document use:
insulin i 125
blood and hemopoietic system
glucagon i 125
glucagon i 127
in vitro study
Receptors, Cell Surface
Hormone and Metabolic Research, 14 (2), 65-68