Modulatory effects of quercetin on proliferation and differentiation of the human colorectal cell line Caco-2

Title

Modulatory effects of quercetin on proliferation and differentiation of the human colorectal cell line Caco-2

 Author

Dihal, A.A.
Woutersen, R.A.
Ommen, B.v.
Rietjens, I.M.C.M.
Stierum, R.H.
TNO Kwaliteit van Leven

Publication year

2006

 Abstract

The effect of the dietary flavonoid quercetin was investigated on proliferation and differentiation of the human colon cancer cell line Caco-2. Confluent Caco-2 monolayers exposed to quercetin showed a biphasic effect on cell proliferation and a decrease in cell differentiation (0.001 Subject

Biology
Toxicology and Applied Pharmacology
Caco-2
Colorectal cancer
Differentiation
Metabolism
Proliferation
Quercetin
3' o methylquercetin 4' o glucuronide
3' o methylquercetin 7 o sulfate
4' o methylquercetin 3' o glucuronide
4' o methylquercetin 7 o glucuronide
isorhamnetin
quercetin
quercetin derivative
unclassified drug
article
cell differentiation
cell proliferation
cell strain CACO 2
controlled study
human
human cell
priority journal
statistical significance
Anticarcinogenic Agents
Caco-2 Cells
Cell Differentiation
Cell Proliferation
Colorectal Neoplasms
Drug Stability
Humans
Quercetin

 To reference this document use:

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 DOI

https://doi.org/10.1016/j.canlet.2005.07.007

 TNO identifier

239375

 ISSN

0304-3835

 Source

Cancer Letters, 238 (2), 248-259

 Document type

article
Files
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