Print Email Facebook Twitter Assessment of dermal exposure of greenhouse workers to the pesticide bupirimate Title Assessment of dermal exposure of greenhouse workers to the pesticide bupirimate Author Medisch Biologisch Laboratorium TNO Jongen, M.J.M. Engel, R. Leenheers, L.H. Publication year 1992 Abstract An HPLC method was developed for estimation of dermal exposure of greenhouse workers to the pesticide bupirimate. Chromatography was performed on a cyano-modified silica column with methanol-water (6:4 by volume) containing 5 g/L ammonium sulfate as eluent. UV detection at 310 nm was used for quantitation. Dermal exposure was assessed by letting the workers wear cotton gloves and by measuring foliar dislodgable residues in the greenhouses as potential exposure. The analytical procedure was validated for measurement of bupirimate on cotton gloves and in solutions used for the estimation of foliar dislodgable residues. Gloves were extracted with methanol. Recovery of bupirimate from fortified gloves was complete. Methanol extracts with one volume of water added and solutions containing dislodgable residues were injected directly onto the HPLC system. The limit of detection was 30 μg/L. Between-day coefficients of variation were 7 and 4% at concentrations of 0.6 and 28 mg/L, respectively. Chemicals/CAS: ammonium sulfate, 7783-20-2; bupirimate, 41483-43-6; methanol, 67-56-1; bupirimate, 41483-43-6; Mesylates; Pesticide Residues. Subject Ammonium sulfateBupirimateFungicideMethanolPesticideUnclassified drugExtractionGloveHigh performance liquid chromatographyHumanOccupational exposurePriority journalResidue analysisSkin permeabilityUltraviolet spectrophotometryAdministration, CutaneousAdultChromatography, High Pressure LiquidHumanMesylatesOccupational ExposurePesticide ResiduesPlantsSpectrophotometrySupport, Non-U.S. Gov't To reference this document use: http://resolver.tudelft.nl/uuid:540d9124-0018-4709-83cb-3350241dd4fa TNO identifier 231831 ISSN 0146-4760 Source Journal of Analytical Toxicology, 16 (16), 60-62 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.