Print Email Facebook Twitter Safety evaluation of yeast grown on hydrocarbons. II: One-year feeding study in rats with yeast grown on pure n-paraffins Title Safety evaluation of yeast grown on hydrocarbons. II: One-year feeding study in rats with yeast grown on pure n-paraffins Author de Groot, A.P. Til, H.P. Feron, V.J. Centraal Instituut voor Voedingsonderzoek TNO Publication year 1970 Abstract Yeast grown on hydrocarbons according to the n-paraffin process of The British Petroleum Company Ltd. was fed to groups of male and female rats at dietary levels of 10, 20 and 30% for 1 yr. Two control diets were used, one being similar to the yeast diet but with soya-bean meal substituted for yeast and the other being the institute's stock diet. The inclusion of the yeast in the diet did not affect mortality, general condition or behaviour, gain in body weight, or food intake. Haematological values and blood biochemistry were not affected by the consumption of the yeast. There was no evidence of impaired kidney function or of changes in urine composition. No effects related to treatment were revealed by the weights of the principal organs nor by extensive gross and microscopie pathological examinations. This investigation indicates, therefore, that yeast grown on pure n-paraffins by the BP process does not induce any deleterious effects when fed to rats at dietary levels up to 30% for 1 yr. Subject Hemoglobin determinationUrineAnimal FeedAspartate AminotransferasesBody weightDietErythrocyte CountHematocritHemoglobinometryHydrocarbonsKidney Function TestsLeukocyte CountOrgan weightParaffinRatsYeastsOilsLipids To reference this document use: http://resolver.tudelft.nl/uuid:540377ac-7174-4bac-860f-7cf2b6ed457e TNO identifier 280802 ISSN 0015-6264 Source Food and Cosmetics Toxicology, 8 (5), 499-507 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.