Print Email Facebook Twitter Selenium in diet, blood, and toenails in relation to breast cancer: A case-control study Title Selenium in diet, blood, and toenails in relation to breast cancer: A case-control study Author van 't Veer, P. van der Wielen, R.P.J. Kok, F.J. Hermus, R.J.J. Sturmans, F. Centraal Instituut voor Voedingsonderzoek TNO Publication year 1990 Abstract The association between breast cancer and selenium, measured in the diet, plasma, erythrocytes, and toenails, was investigated in a case-control study in the Netherlands during 1985-1987. Dietary selenium intake was assessed by a structured dietary history technique among 133 breast cancer cases and 238 population controls. Absolute and energy-adjusted selenium intake and selenium concentrations in plasma, erythrocytes, and toenails were similar in cases and controls. The multivariate adjusted odds ratios of breast cancer for subjects in the lowest quartile compared with the highest quartile were 1.6 (95% confidence interval (CI) 0.8-3.4) for dietary selenium, 2.0 (95% CI 0.9-4.4) for plasma selenium, 0.9 (95% CI 0.4-1.9) for erythrocyte selenium, and 1.1 (95% CI 0.6-2.1) for toenail selenium. No statistically significant trend was observed in the odds ratios for any of the four indicators of selenium. These results do not suggest a substantial association between selenium and breast cancer for both short- and long-term markers of selenium status. Chemicals/CAS: selenium, 7782-49-2; Selenium, 7782-49-2 Subject breast neoplasmsdieterythrocytesplasmaseleniumseleniumarticleblood levelbreast cancerdieterythrocytefemalehumannailpriority journaltoeAdultBreast NeoplasmsCase-Control StudiesDietErythrocytesFemaleHumanMiddle AgeNailsNetherlandsOdds RatioSeleniumSupport, Non-U.S. Gov'tToes To reference this document use: http://resolver.tudelft.nl/uuid:4d9a2ac3-0a29-44a9-bdd9-d623f441c106 TNO identifier 231055 ISSN 0002-9262 Source American Journal of Epidemiology, 131 (6), 987-994 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.