Title
Harmonization of description and classification of fetal observations: Achievements and problems still unresolved. Report of the 7th Workshop on the Terminology in Developmental Toxicology Berlin, 4-6 May 2011
Author
Solecki, R.
Barbellion, S.
Bergmann, B.
Bürgin, H.
Buschmann, J.
Clark, R.
Comotto, L.
Fuchs, A.
Faqi, A.S.
Gerspach, R.
Grote, K.
Hakansson, H.
Heinrich, V.
Heinrich-Hirsch, B.
Hofmann, T.
Hübel, U.
Inazaki, T.H.
Khalil, S.
Knudsen, T.B.
Kudicke, S.
Lingk, W.
Makris, S.
Müller, S.
Paumgartten, F.
Pfeil, R.
Rama, E.M.
Schneider, S.
Shiota, K.
Tamborini, E.
Tegelenbosch, M.
Ulbrich, B.
van Duijnhoven, E.A.J.
Wise, D.
Chahoud, I.
Publication year
2013
Abstract
This article summarizes the 7th Workshop on the Terminology in Developmental Toxicology held in Berlin, May 4-6, 2011. The series of Berlin Workshops has been mainly concerned with the harmonization of terminology and classification of fetal anomalies in developmental toxicity studies. The main topics of the 7th Workshop were knowledge on the fate of anomalies after birth, use of Version 2 terminology for maternal-fetal observations and non-routinely used species, reclassification of " grey zone" anomalies and categorization of fetal observations for human health risk assessment.The paucity of data on health consequences of the postnatal permanence of fetal anomalies is relevant and further studies are needed. The Version 2 terminology is an important step forward and the terms listed in this glossary are considered also to be appropriate for most observations in non-routinely used species.Continuation of the Berlin Workshops was recommended. Topics suggested for the next Workshop were grouping of fetal observations for reporting and statistical analysis. © 2012 Elsevier Inc.
Subject
Triskelion BV
TARA - Toxicology and Risk Assessment
TNO Bedrijven
Biology
Information Society
Developmental toxicology
Grey zone anomalies
Malformation
Non-human primates
Reproductive toxicology
Terminology glossary
Variation
To reference this document use:
http://resolver.tudelft.nl/uuid:4822c234-314f-40a5-97ca-2108d2e11905
DOI
https://doi.org/10.1016/j.reprotox.2012.06.006
TNO identifier
469140
ISSN
0890-6238
Source
Reproductive Toxicology, 35 (1), 48-55
Document type
article