Print Email Facebook Twitter Characterization of some synthetic Ru and Ir complexes by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry Title Characterization of some synthetic Ru and Ir complexes by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry Author Lou, X. van Buijtenen, J. Bastiaansen, J.J.A.M. de Waal, B.F.M. Langeveld, B.M.W. van Dongen, J.L.J. TNO Industrie en Techniek Publication year 2005 Abstract Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) was applied to the analysis of Ru(OCOCF 3)2(CO)(PPh3)2, Ru(OCOC 3F7)2(CO)(PPh3)2, Ir(tBuppy)3 and Ir(ppy)2(acac) complexes. A troublesome problem in the MALDI-TOFMS characterization of these metal complexes is the possible replacement of complex ligands by matrix. In this contribution, 10 matrices, ranging from acidic to basic, were investigated: α-cyano-4- hydroxycinnamic acid (CHCA), 2,5-dihydroxybenzoic acid (DHB), sinapinic acid (SA), dithranol, 2,4,6-trihydroxyactophenone (THAP), 6-azo-2-thiothymine (ATT), norharman, 2-[(2E)-3-(4-tert-butylphenyl)-2-methylprop-2-enylidene]malononitrile (DCTB), 4-nitroaniline (NA) and 2-amino-5-nitrophyridine (ANP). With most of the matrices, including the neutral and basic ones, matrix substitution of ligand could clearly be detected. Based on the experimental results, possible mechanisms of matrix substitution were discussed. It was demonstrated that the ligand exchange process might also occur through the gas-phase reactions initiated by laser shots. Among the matrices tested, DCTB was found to be the best one for the complexes that are prone to ligand exchange by matrix. Subject MachinesIridium complexMatrix-assisted laser desorption/ionization mass spectrometryRuthenium complexAcidityCarboxylic acidsComplexationDesorptionLaser applicationsReaction kineticsRuthenium compoundsLigandsSinapinic acidTime-of-flight mass spectrometry (TOFMS)Alpha cyano 4 hydroxycinnamic acidAzo compoundBenzene derivativeBeta carbolineBipyridine derivativeDithranolGentisic acidHydroxyl groupMalononitrileNitro derivativePyridine derivativeThymine derivativeAlkalinityAnalytic method To reference this document use: http://resolver.tudelft.nl/uuid:47f1acf0-a319-4c8a-8962-72d620f92524 TNO identifier 238473 Publisher Wiley ISSN 1076-5174 Source Journal of Mass Spectrometry, 40 (5), 654-660 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.