Zebrafish as potential model for developmental neurotoxicity testing: A mini review

Title

Zebrafish as potential model for developmental neurotoxicity testing: A mini review

 Author

de Esch, C.
Slieker, R.
Wolterbeek, A.
Woutersen, R.
de Groot, D.

Publication year

2012

 Abstract

The zebrafish is a powerful toxicity model; biochemical assays can be combined with observations at a structural and functional level within one individual. This mini review summarises the potency of zebrafish as a model for developmental neurotoxicity screening, and its possibilities to investigate working mechanisms of toxicants. The use of zebrafish in toxicity research can ultimately lead to the refinement or reduction of animal use. © 2012 Elsevier Inc. All rights reserved.

 Subject

Life
QS - Quality & Safety
EELS - Earth, Environmental and Life Sciences
Biomedical Innovation
Biology
Healthy Living
Zebrafish
Toxicity screening
Developmental neurotoxicity
Model

 To reference this document use:

http://resolver.tudelft.nl/uuid:45dd74a9-fda0-47f6-a928-bc364c5cadc2

 DOI

https://doi.org/10.1016/j.ntt.2012.08.006

 TNO identifier

472503

 Source

Neurotoxicology and Teratology, 34 (6), 545-553

 Document type

article
Files
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