Title
Silicon dioxide and titanium dioxide particles found in human tissues
Author
Peters, R.J.B.
Oomen, A.G.
van Bemmel, G.
van Vliet, L.
Undas, A.K.
Munniks, S.
Bleys, R.L.A.W.
Tromp, P.C.
Brand, W.
van der Lee, M.
Publication year
2020
Abstract
Silicon dioxide (silica, SiO2, SAS) and titanium dioxide (TiO2) are produced in high volumes and applied in many consumer and food products. As a consequence, there is a potential human exposure and subsequent systemic uptake of these particles. In this study we show the characterization and quantification of both total silicon (Si) and titanium (Ti), and particulate SiO2 and TiO2 in postmortem tissue samples from 15 deceased persons. Included tissues are liver, spleen, kidney and the intestinal tissues jejunum and ileum. Low-level analysis was enabled by the use of fully validated sample digestion methods combined with (single particle) inductively coupled plasma high resolution mass spectrometry techniques (spICP-HRMS). The results show a total-Si concentration ranging from
Subject
Silicon dioxide
Titanium dioxide
Silica
Human tissue
Nanoparticle
Single particle ICP-MS
Environment & Sustainability
Urbanisation
To reference this document use:
http://resolver.tudelft.nl/uuid:3a36cf7f-cacd-4870-9356-6b6ab30daba9
DOI
https://doi.org/10.1080/17435390.2020.1718232
TNO identifier
873522
Publisher
Taylor and Francis Ltd
ISSN
1743-5390
Source
Nanotoxicology, 1-14
Document type
article