Title
Comprehensive two-dimensional liquid chromatography and hyphenated liquid chromatography to study the degradation of poly(bisphenol A)carbonate
Author
Coulier, L.
Kaal, E.R.
Hankemeier, T.
TNO Kwaliteit van Leven
Publication year
2005
Abstract
Size exclusion chromatography (SEC), gradient polymer elution chromatography (GPEC) and liquid chromatography at critical conditions (LC-CC) have been developed and applied to observe chemical changes in poly(bisphenol A)carbonate (PC) due to hydrolytic degradation. Especially LC-CC appeared to be very successful to observe differences in functionality of PC as result of hydrolytic degradation. Observed differences due to degradation could be identified by (semi) on-line coupling to matrix assisted laser desorption-ionization time-of-flight mass spectrometry (MALDI-TOF-MS). The differences in functionality could be attributed to the formation of different end-groups, i.e. OH end-groups. In addition, comprehensive two-dimensional liquid chromatography (2D-LC) has been applied successfully to study the hydrolytic degradation of PC. LC-CC x SEC showed that the formation of PC with different end-groups occurred over the whole molecular mass range. This information could not be obtained with the separate liquid chromatographic techniques, thereby illustrating the added value of 2D-LC. © 2005 Elsevier B.V. All rights reserved.
Subject
Packaging
Analytical research
Degradation
GPEC
LC x SEC
LC-CC
MALDI-TOF-MS
Poly(bisphenol A)carbonate
Two-dimensional liquid chromatography
Alcohols
Biodegradation
Hydrolysis
Molecular weight
Polymers
Size exclusion chromatography
Gradient polymer elution chromatography (GPEC)
Hydrolytic degradation
Molecular mass
Liquid chromatography
4,4' isopropylidenediphenol
carbonic acid derivative
analytic method
article
chemical reaction kinetics
gel permeation chromatography
hydrolysis kinetics
liquid chromatography
matrix assisted laser desorption ionization time of flight mass spectrometry
molecular weight
priority journal
Chromatography, Gel
Polymers
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Spectrophotometry, Ultraviolet
To reference this document use:
http://resolver.tudelft.nl/uuid:3981e83e-7efb-461f-973f-62d5ffe9dba7
DOI
https://doi.org/10.1016/j.chroma.2005.02.067
TNO identifier
238432
ISSN
0021-9673
Source
Journal of Chromatography A, 1070 (1-2), 79-87
Document type
article