Title
Transient hypothyroxinaemia associated with developmental delay in very preterm infants
Author
Meijer, W.J.
Verloove-Vanhorick, S.P.
Brand, R.
van den Brande, J.L.
TNO Preventie en Gezondheid
Publication year
1992
Abstract
In 563 surviving very preterm (<32 weeks gestational age) and/or very low birthweight (<1500 g) infants the relationship between neonatal thyroxine concentration and psychomotor development at 2 years of age (corrected for preterm birth) was studied. A significant association was found between low neonatal thyroxine concentration and a negative score on the three milestones of development. These findings do not support the view that transient hypothyroxinaemia in preterm infants is harmless. Chemicals/CAS: thyroxine, 7488-70-2; Thyroxine, 7488-70-2
Subject
Thyroxine
Child
Child development
Female
Male
Major clinical study
Newborn
Prematurity
Preschool child
Psychomotor development
Thyroxine blood level
Very low birth weight
Child, Preschool
Developmental Disabilities
Follow-Up Studies
Human
Hypothyroidism
Infant
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature
Logistic Models
Odds Ratio
Psychomotor Performance
Thyroxine
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TNO identifier
231749
ISSN
0003-9888
Source
Archives of Disease in Childhood, 67 (7), 944-947
Document type
article