Print Email Facebook Twitter The Disease-Modifying Role of Taurine and Its Therapeutic Potential in Coronavirus Disease 2019 (COVID-19) Title The Disease-Modifying Role of Taurine and Its Therapeutic Potential in Coronavirus Disease 2019 (COVID-19) Author van Eijk, L.E. Offringa, A.K. Bernal, M.E. Bourgonje, A.R. van Goor, H. Hillebrands, J.L. Publication year 2022 Abstract Taurine is an amino sulfonic acid that is implicated in numerous physiological functions, including the regulation of oxidative stress, which plays an important role in coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), together with other pathophysiological processes. The recent finding of decreased serum taurine levels in SARS-CoV-2-infected patients, in tandem with its potential modulatory role in COVID-19 due to its antiviral, antioxidant, anti-inflammatory, and vascular-related effects, provides a rationale for considering taurine as a beneficial supplement in patients suffering from COVID-19. Here, we reviewed the potential disease-modifying effects of taurine and combined these with the current knowledge on COVID-19 to clarify the potential role of taurine in this respiratory disease. Subject TaurineCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Oxidative stressInflammationTreatment To reference this document use: http://resolver.tudelft.nl/uuid:28ec7bbd-82f2-48d9-bc97-cf71d8a79135 DOI https://doi.org/10.1007/978-3-030-93337-1_1 TNO identifier 973513 ISSN 0065-2598 Source Advances in experimental medicine and biology, 1370 (1370), 3-21 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.