Title
The Disease-Modifying Role of Taurine and Its Therapeutic Potential in Coronavirus Disease 2019 (COVID-19)
Author
van Eijk, L.E.
Offringa, A.K.
Bernal, M.E.
Bourgonje, A.R.
van Goor, H.
Hillebrands, J.L.
Publication year
2022
Abstract
Taurine is an amino sulfonic acid that is implicated in numerous physiological functions, including the regulation of oxidative stress, which plays an important role in coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), together with other pathophysiological processes. The recent finding of decreased serum taurine levels in SARS-CoV-2-infected patients, in tandem with its potential modulatory role in COVID-19 due to its antiviral, antioxidant, anti-inflammatory, and vascular-related effects, provides a rationale for considering taurine as a beneficial supplement in patients suffering from COVID-19. Here, we reviewed the potential disease-modifying effects of taurine and combined these with the current knowledge on COVID-19 to clarify the potential role of taurine in this respiratory disease.
Subject
Taurine
Coronavirus disease 2019 (COVID-19)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Oxidative stress
Inflammation
Treatment
To reference this document use:
http://resolver.tudelft.nl/uuid:28ec7bbd-82f2-48d9-bc97-cf71d8a79135
DOI
https://doi.org/10.1007/978-3-030-93337-1_1
TNO identifier
973513
ISSN
0065-2598
Source
Advances in experimental medicine and biology, 1370 (1370), 3-21
Document type
article