Title
Use of qualitative and quantitative fluorescence techniques to assess dermal exposure
Author
Cherrie, J.W.
Brouwer, D.H.
Roff, M.
Vermeulen, R.
Kromhout, H.
Publication year
2000
Abstract
Fluorescent tracers provide a way of simultaneously assessing the mass of a contaminant hazardous substance on the surface of the skin of a worker and the area of skin exposed. These parameters, along with the duration of exposure and the estimated contaminant concentration in the skin contamination layer, can be used to calculate the likely uptake through the skin. Repeated assessment of the mass of tracer on a surface within a room or on the surface of the skin can also allow the net transfer of contaminant to that compartment to be estimated. Qualitative evaluation of transfer processes using fluorescent tracers can help identify important secondary sources of exposure. (C) 2000 British Occupational Hygiene Society. Fluorescent tracers provide a way of simultaneously assessing the mass of a contaminant hazardous substance on the surface of the skin of a worker and the area of skin exposed. These parameters, along with the duration of exposure and the estimated contaminant concentration in the skin contamination layer, can be used to calculate the likely uptake through the skin. Repeated assessment of the mass of tracer on a surface within a room or on the surface of the skin can also allow the net transfer of contaminant to that compartment to be estimated. Qualitative evaluation of transfer processes using fluorescent tracers can help identify important secondary sources of exposure. Chemicals/CAS: Fluorescent Dyes
Subject
Workplace
Contamination
Skin
Toxic materials
Trace analysis
Dermal exposure
Fluorescent tracers
Industrial hygiene
Analytic method
Fluorescence
Occupational hazard
Skin surface
Environmental Monitoring
Fluorescent Dyes
Human
Models, Biological
Occupational Exposure
Research Design
Risk Assessment
Skin Absorption
Time Factors
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TNO identifier
87323
Source
Annals of Occupational Hygiene, 44 (7), 519-522
Document type
article