Neural representations of haptic object size in the human brain revealed by multivoxel fMRI patterns

Neural representations of haptic object size in the human brain revealed by multivoxel fMRI patterns

Perini, F.
Powell, T.
Watt, S.J.
Downing, P.E.

2020

The brain must interpret sensory input from diverse receptor systems to estimate object properties. Much has been learned about the brain mechanisms behind these processes in vision, but our understanding of haptic perception remains less clear. Here we examined haptic judgments of object size, which require integrating multiple cutaneous and proprioceptive afferent signals, as a model problem. To identify candidate human brain regions that support this process, participants (n = 16) in an event-related functional MRI experiment grasped objects to categorize them as one of four sizes. Object sizes were calibrated psychophysically to be equally distinct for each participant. We applied representational similarity logic to whole brain, multivoxel searchlight analyses to identify brain regions that exhibit size-relevant voxelwise activity patterns. Of particular interest was to identify regions for which more similar sizes produce more similar patterns of activity, which constitutes evidence of a metric size code. Regions of the intraparietal sulcus and the lateral prefrontal cortex met this criterion, both within hands and across hands. We suggest that these regions compute representations of haptic size that abstract over the specific peripheral afferent signals generated in a grasp. Results of a matched visual size task, performed by the same participants and analyzed in the same fashion, identified similar regions, indicating that these representations may be partly modality general. We consider these results with respect to perspectives on magnitude estimation in general and to computational views on perceptual signal integration.NEW & NOTEWORTHY Our understanding of the neural basis of haptics (perceiving the world through touch) remains incomplete. We used functional MRI to study human haptic judgments of object size, which require integrating multiple afferent signals. Multivoxel pattern analyses identified intraparietal and prefrontal regions that encode size haptically in a metric and hand-invariant fashion. Effector-independent haptic size estimates are useful on their own and in combination with other sensory estimates for a variety of perceptual and motor tasks.

functional MRI
haptics
multivoxel pattern analysis
size estimation
adult
abrain region
clinical article
controlled study
decision making
female
functional magnetic resonance imaging
human
human experiment
intraparietal sulcus
lateral prefrontal cortex
logic
male
skin

http://resolver.tudelft.nl/uuid:21692e89-0f38-40a9-9cf4-6208acd6769c

878390

NLM (Medline)

1522-1598

Journal of neurophysiology, 124 (1), 218-231

article