Print Email Facebook Twitter The Cough Cylinder: A tool to study measures against airborne spread of (myco-) bacteria Title The Cough Cylinder: A tool to study measures against airborne spread of (myco-) bacteria Author van den Driessche, K. Marais, B.J. Wattenberg, M. Magis-Escurra, C. Reijers, M. Tuinman, I.L. Boeree, M.J. van Soolingen, D. de Groot, R. Cotton, M.F. Publication year 2013 Abstract BACKGROUND: 'Covering your cough' reduces droplet number, but its effect on airborne pathogen transmission is less clear. The World Health Organization specifically recommends cough etiquette to prevent the spread of Mycobacterium tuberculosis, but implementation is generally poor and evidence supporting its value is lacking. METHODS: We constructed a model to assess 'real life' transmission risk by counting viable pathogens from aerosols produced by coughing patients, thus allowing the assessment of outward protection measures in a standardised fashion. During the validation process, we focused on rod-shaped bacteria as surrogates for M. tuberculosis. RESULTS: The Cough Cylinder enabled us to sample Pseudomonas aeruginosa, Escherichia coli and mycobacteria from aerosols produced by patients with cystic fibrosis, primary ciliary dyskinesia and tuberculosis. Pathogens in droplets and in airborne particles could be sampled. Delayed air sampling allowed specific measurement of persistent airborne particles. CONCLUSION: This novel experimental system allows measurement of aerosol pathogen spread in a highly standardised fashion. It also offers the possibility to assess the impact of different interventions to limit aerosol transmission. © 2013 The Union. Subject LifeCBRN - CBRN ProtectionEELS - Earth, Environmental and Life SciencesBiologyIndustrial InnovationAerosol transmissionCough etiquetteInfection controlRespiratory hygieneTuberculosis To reference this document use: http://resolver.tudelft.nl/uuid:1f3cc03e-d1b2-4e56-b96f-a4d8ce41b108 DOI https://doi.org/10.5588/ijtld.12.0289 TNO identifier 466853 ISSN 1027-3719 Source International Journal of Tuberculosis and Lung Disease, 17 (1) Document type article Files To receive the publication files, please send an e-mail request to TNO Library.