Title
Are coffee, tea and total fluid consumption associated with bladder cancer risk? Results from the Netherlands Cohort Study
Author
Zeegers, M.P.A.
Dorant, E.
Goldbohm, R.A.
van den Brandt, P.A.
Centraal Instituut voor Voedingsonderzoek TNO
Publication year
2001
Abstract
Objectives: Coffee, tea, and fluid consumption have been thought to influence bladder cancer incidence. In a large prospective study, these associations were investigated. Methods: In 1986, cohort members (55-69 years) completed a questionnaire on cancer risk factors. Follow-up was established by linkage to cancer registries until 1992. The multivariable case-cohort analysis was based on 569 bladder cancer cases and 3123 subcohort members. Results: The incidence rate ratios (RR) for men consuming < 2 cups of coffee/day was 0.89 (95% CI 0.51-1.5) using the median consumption category (4-< 5 cups/day) as reference. This RR increased to 1.3 (95% CI 0.94-1.9) for men consuming ≥7 cups/day, although no clear dose-response association was found. The RRs decreased from 1.2 (95% CI 0.56-2.7) for women consuming <2 cups of coffee/day to 0.36 (95% CI 0.18-0.72) for women consuming ≥5 cups/day compared to the median consumption category (3-<4 cups/day). Men and women who abstained from drinking tea had a RR of 1.3 (95% CI 0.97-1.8) compared to those consuming 2-<3 cups of tea per day (median consumption c category). The RR for men and women comparing highest to lowest quintile of total fluid consumption was 0.87 (95% CI 0.63-1.2). Conclusion: The data suggest a possible positive association between coffee consumption and bladder cancer risk in men and a probable inverse association in women. Tea consumption was inversely associated with bladder cancer. Total fluid consumption did not appear to be associated with bladder cancer.
Subject
Nutrition
Aged
Beverages
Coffee
Drinking
Female
Follow-Up Studies
Humans
Male
Middle Aged
Multivariate Analysis
Netherlands
Odds Ratio
Prospective Studies
Questionnaires
Risk
Risk Factors
Tea
Urinary Bladder Neoplasms
To reference this document use:
http://resolver.tudelft.nl/uuid:1ed4480f-5aeb-450c-87cd-477a178f505c
DOI
https://doi.org/10.1023/a:1011245627593
TNO identifier
87499
ISSN
0957-5243
Source
Cancer Causes and Control, 12 (3), 231-238
Document type
article