Print Email Facebook Twitter Multi-locus control of MLC reactions in rhesus monkeys Title Multi-locus control of MLC reactions in rhesus monkeys Author Widmer, M.B. Balner, H. Primatencentrum TNO Publication year 1978 Abstract The genetic basis for MLC reactivity in rhesus monkeys was further investigated. Cells from an intra-RhLA recombinant monkey were MLC reactive with those of an SD-identical sib and with each of two sets of homozygous typing cells carrying either paternal haplotype. Also, cells from a pair of RhLA- identical sibs reacted in MLC with each other, as well as with three genotypically different siblings. This excludes control of MLC reactivity by the conventional D locus only. Thus the results selected for presentation provide formal evidence for the existence of at least one additional MLC locus, named D′. The possibility that D′ exerts its influence on MLC reactivity only after alloimmunization is discussed. Subject animal experimentblood and hemopoietic systemgene controlheredityin vitro studymixed lymphocyte reactionmonkeyserologically defined antigen To reference this document use: http://resolver.tudelft.nl/uuid:18a3e74b-ad8e-4c25-8f94-d73c7db35f53 DOI https://doi.org/10.1007/bf01844001 TNO identifier 228445 ISSN 0093-7711 Source Immunogenetics, 7 (2), 155-164 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.