Print Email Facebook Twitter Hypertension and road traffic noise exposure Title Hypertension and road traffic noise exposure Author de Kluizenaar, Y. Gansevoort, R.T. Miedema, H.M.E. de Jong, P.E. TNO Bouw en Ondergrond Publication year 2007 Abstract OBJECTIVE: The purpose of this study was to assess the relationship between road traffic noise exposure at home and the prevalence of hypertension. METHODS: We conducted cross-sectional analyses in a large random sample (N = 40,856) of inhabitants of Groningen City, and in a subsample (the Prevention of Renal and Vascular End-Stage Disease [PREVEND]) study cohort; N = 8592). RESULTS: Before adjustment for confounders, road traffic noise exposure was associated with self-reported use of antihypertensive medication in the city of Groningen sample (odds ratio [OR] = 1.31 per 10-dB increase in Lden). Adjusted odds ratios were significant for the subjects between 45 and 55 years old in the full model when adjusted for PM10 (OR = 1.19) and at higher exposure (Lden >55 dB) only (OR = 1.21; with adjustment for PM10, OR = 1.31). In the PREVEND cohort, the unadjusted odds ratio was 1.35 for hypertension (systolic and diastolic blood pressure >140 and >90 mm Hg, respectively, or use of antihypertensive medication). Again, the adjusted odds ratio was significant for subjects between 45 and 55 years old (OR = 1.27; with adjustment for PM10, OR = 1.39). CONCLUSIONS: Exposure to road traffic noise may be associated with hypertension in subjects who are between 45 and 55 years old. Associations seemed to be stronger at higher noise levels. ©2007The American College of Occupational and Environmental Medicine. Subject Health Trafficantihypertensive agentadultagedantihypertensive therapyarticlecohort analysiscontrolled studycross-sectional studydiastolic blood pressuredisease associationenvironmental exposurefemalehumanhypertensionmajor clinical studymaleprevalenceprevention studyrandom samplerisk assessmentself reportsystolic blood pressuretraffic noiseAdultAgedAutomobilesCohort StudiesEnvironmental MonitoringFemaleHumansHypertensionMaleMiddle AgedNetherlandsNoise, TransportationOdds RatioQuestionnaires To reference this document use: http://resolver.tudelft.nl/uuid:0d37bab5-08ea-45ba-885e-e6f04ed78620 DOI https://doi.org/10.1097/jom.0b013e318058a9ff TNO identifier 239963 ISSN 1076-2752 Source Journal of Occupational and Environmental Medicine, 49 (5), 484-492 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.