Title
Effect of bioprocessing of wheat bran in wholemeal wheat breads on the colonic SCFA production in vitro and postprandial plasma concentrations in men
Author
Mateo Anson, N.
Havenaar, R.
Vaes, W.
Coulier, L.
Venema, K.
Selinheimo, E.
Bast, A.
Haenen, G.R.M.M.
Publication year
2011
Abstract
The health benefits of whole grain consumption can be partly attributed to the inclusion of the bran or outer-layers of the grain rich in dietary fibre. Fibre is fermented in the colon, leading to the production of beneficial metabolites, such as short-chain fatty acids (SCFA). The effect of five different types of bread on the SCFA production was studied in an in vitro model of human colon. Additionally, the postprandial effects of two selected breads on the SCFA plasma concentrations were investigated in men. A higher in vitro production of butyrate was induced by wholemeal wheat bread with bioprocessed bran than by native bran. The increase in butyrate seemed to be in exchange for propionate, whilst the total SCFA production remained similar. However, differences between the two breads in the postprandial butyrate concentrations could not be detected in peripheral blood of men, probably due to an effective utilisation by colonocytes. © 2011 Elsevier Ltd. All rights reserved.
Subject
Life
QS - Quality & Safety PHS - Pharmacokinetics & Human Studies
EELS - Earth, Environmental and Life Sciences
Nutrition
Bioprocessing
Butyrate
Fibre
Wheat bran
To reference this document use:
http://resolver.tudelft.nl/uuid:08003d31-7671-4300-9316-71a3f2b453c2
DOI
https://doi.org/10.1016/j.foodchem.2011.03.043
TNO identifier
429691
ISSN
0308-8146
Source
Food Chemistry, 128 (2), 404-409
Document type
article