Print Email Facebook Twitter Radiosensitization of biologically active DNA in cellular extracts by oxygen. Evidence that the presence of SH compounds is not required Title Radiosensitization of biologically active DNA in cellular extracts by oxygen. Evidence that the presence of SH compounds is not required Author van Hemmen, J.J. Meuling, W.J.A. Bleichrodt, J.F. Medisch Biologisch Laboratorium TNO Publication year 1974 Abstract The radiosensitization by oxygen of biologically active bacteriophage DNA in bacterial extracts was studied. The oxygen effect in such a system appeared not to be due or only to a minor extent to the presence of endogenous sulphydryl compounds. The components in a cell extract which enable oxygen and other sensitizers to sensitize DNA could not be destroyed by extremely high doses of γ radiation. Chemicals/CAS: DNA, 9007-49-2; oxygen, 7782-44-7; thiol derivative, 13940-21-1; Azo Compounds; Cobalt Radioisotopes; Cyclic N-Oxides; Cysteamine, 60-23-1; DNA, Circular; DNA, Viral; Ethylmaleimide, 128-53-0; Oxygen, 7782-44-7; Radiation-Sensitizing Agents; Sulfhydryl Compounds Subject BiologyBacteriophage dnaDNAOxygenRadioisotopeThiol derivativeGamma radiationIn vitro studyMethodologyMicroorganismRadiosensitivityRadiosensitizationTheoretical studyAzo CompoundsCobalt RadioisotopesColiphagesCyclic N-OxidesCysteamineDNA VirusesDNA, CircularDNA, ViralDose-Response Relationship, RadiationEscherichia coliEthylmaleimideGamma RaysMutationOxygenPseudomonasRadiation EffectsRadiation-Sensitizing AgentsSulfhydryl Compounds To reference this document use: http://resolver.tudelft.nl/uuid:f8b2232b-2515-4dae-903f-6f0cd00d51d5 TNO identifier 227740 ISSN 0955-3002 Source International Journal of Radiation Biology, 26 (6), 547-555 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.