Print Email Facebook Twitter Solubility of fumaric acid and its monosodium salt Title Solubility of fumaric acid and its monosodium salt Author Roa Engel, C.A. ter Horst, J.H. Pieterse, M. van der Wielen, L.A.M. Straathof, A.J.J. Publication year 2013 Abstract Fumaric acid is a dicarboxylic acid applied in food industry and in some polymers. Currently, its fermentative production from renewable resources is receiving much attention, and crystallization is used to recover it. To determine the window of operation for crystallization from multicomponent fermentation mixtures, the aqueous solubilities of fumaric acid and its sodium salts were investigated. For fumaric acid, sodium hydrogen fumarate, and sodium fumarate, solubilities and pH increased in this order because of increasing polarity and dissociation. A mathematical model was developed to predict crystal type and amount as function of temperature and pH. The effect of glucose (up to 3.0 mmol·mol-1) on the solubility can be neglected, but ethanol (1.0 mmol·mol-1) slightly increased the solubility of fumaric acid and significantly decreased the solubility of the sodium salts, because the aqueous solution becomes less polar upon ethanol addition but not upon glucose addition. © 2013 American Chemical Society. Subject Fluid Mechanics Chemistry & EnergeticsPID - Process & Instrumentation DevelopmentTS - Technical SciencesChemistryIndustrial InnovationAqueous solubilityDicarboxylic acidEthanol additionFermentative productionFood industriesGlucose additionMonosodium saltsRenewable resourceEthanolGlucoseMathematical modelsSaltsSolubility To reference this document use: http://resolver.tudelft.nl/uuid:b884fa0a-7156-42a7-9bc5-689a2ce7c718 TNO identifier 478211 ISSN 0888-5885 Source Industrial and Engineering Chemistry Research, 52 (27), 9454-9460 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.