Title
Alcohol consumption and risk of type 2 diabetes among older women
Author
Beulens, J.W.J.
Stolk, R.P.
van der Schouw, Y.T.
Grobbee, D.E.
Hendriks, H.F.J.
Bots, M.L.
TNO Kwaliteit van Leven
Publication year
2005
Abstract
OBJECTIVE - This study aimed to investigate the relation between alcohol consumption and type 2 diabetes among older women. RESEARCH DESIGN AND METHODS - Between 1993 and 1997, 16,330 women aged 49-70 years and free from diabetes were enrolled in one of the Dutch Prospect-EPIC (European Prospective Study Into Cancer and Nutrition) cohorts and followed for 6.2 years (range 0.1-10.1). At enrollment, women filled in questionnaires and blood samples were collected. RESULTS - During follow-up, 760 cases of type 2 diabetes were documented. A linear inverse association (P = 0.007) between alcohol consumption and type 2 diabetes risk was observed, adjusting for potential confounders. Compared with abstainers, the hazard ratio for type 2 diabetes was 0.86 (95% CI 0.66-1.12) for women consuming 5-30 g alcohol per week, 0.66 (0.48-0.91) for 30-70 g per week, 0.91 (0.67-1.24) for 70-140 g per week, 0.64 (0.44-0.93) for 140-210 g per week, and 0.69 (0.47-1.02) for >210 g alcohol per week. Beverage type did not influence this association. Lifetime alcohol consumption was associated with type 2 diabetes in a U-shaped fashion. CONCLUSIONS - Our findings support the evidence of a decreased risk of type 2 diabetes with moderate alcohol consumption and expand this to a population of older women. © 2005 by the American Diabetes Association.
Subject
Health
Biomedical Research
adult
aged
alcohol consumption
article
beverage
blood sampling
controlled study
disease association
female
follow up
hazard assessment
human
major clinical study
non insulin dependent diabetes mellitus
prospective study
questionnaire
beer
blood pressure
body mass
body size
clinical trial
drinking behavior
middle aged
multicenter study
Netherlands
risk assessment
smoking
wine
Aged
Alcohol Drinking
Beer
Blood Pressure
Body Mass Index
Body Size
Diabetes Mellitus, Type 2
Female
Humans
Middle Aged
Netherlands
Questionnaires
Risk Assessment
Smoking
Wine
To reference this document use:
http://resolver.tudelft.nl/uuid:adf053ff-20f1-453d-8a8a-6dde9bb96fe3
DOI
https://doi.org/10.2337/diacare.28.12.2933
TNO identifier
238881
ISSN
0149-5992
Source
Diabetes Care, 28 (12), 2933-2938
Document type
article