Title
Variability of near-fainting responses in healthy 6-16-year-old subjects
Author
de Jong-de Vos Van Steenwijk, C.C.E.
Wieling, W.
Harms, M.P.M.
Wesseling, K.H.
TNO Biomedical Instrumentation
Publication year
1997
Abstract
1. Fainting is a common phenomenon in young subjects, but the final events before the actual faint are not well known. The aim of the present study was to study the inter-individual variability of haemodynamic events associated with near-fainting in children and teenagers. 2. Sixty-eight healthy subjects (aged 6-16 years) performed a 70°tilt-up test with intravascular instrumentation for 5 min. Responses in 29 near-fainting subjects were analysed and compared with 39 non-fainting subjects. Arterial pressure was measured by Finapres. Left ventricular stroke volume was computed from the pressure pulsation wave-form. 3. Inability to maintain vasomotor tone was mechanism underlying near-fainting in the majority of near-fainting subjects. The three classical haemodynamic responses (vasovagal, vasodepressor and vagal) could be recognized, but large individual differences were found. After tilt back, blood pressure in near-fainters showed a mirror response to the stage before tilt-back; blood pressure gradually increased and was normal at 1 min after tilt-back. 4. The variability in haemodynamic responses on approach of an orthostatic faint is wide in the young.
Subject
Health
Orthostasis
Teenagers
Vasomotor system
Adolescent
Blood Pressure
Blood Pressure Monitoring, Ambulatory
Cardiac Output
Child
Electrocardiography
Female
Heart Rate
Hemodynamic Processes
Humans
Hypotension, Orthostatic
Male
Signal Processing, Computer-Assisted
Stroke Volume
Syncope
Tilt-Table Test
Time Factors
Vascular Resistance
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TNO identifier
280504
ISSN
0143-5221
Source
Clinical Science, 93 (3), 205-211
Document type
article