Print Email Facebook Twitter Preterm birth, early growth and adult metabolic health Title Preterm birth, early growth and adult metabolic health Author TNO Kwaliteit van Leven Finken, M.J.J. Publication year 2007 Abstract Children born small-for-gestational-age (SGA) are at risk for short stature, and cardiovascular disease and type 2 diabetes in later life. There is some preliminary evidence for a similar phenotype in survivors of preterm birth. In contrast to children born SGA, preterm infants born appropriate-for-gestational-age who experienced neonatal growth retardation, resulting in a small size at term, are excluded from growth hormone therapy if they fail to catch up in height subsequently. We tested in 19-year-olds born before 32 gestational weeks from the Project On Preterm and Small-for-gestational-age infants cohort the effect of early growth on the growth pattern and adult metabolic health. Childhood growth and adult height were similar in preterm infants born SGA and those with neonatal growth retardation (weight and/or length at 3 months Subject PopsBirth weightBlood pressureBody compositionCarotid intima-media thicknessCortisolGlucocorticoid receptorGrowthInsulin resistanceLipoproteinPreterm birth To reference this document use: http://resolver.tudelft.nl/uuid:732db4dc-b66c-4542-a5f9-c5961f56b6bc TNO identifier 516748 Publisher Universiteit, Leiden ISBN 9789090221663 Document type doctoral thesis Files PDF finken-2007-preterm.pdf