Title
The effects of physical activity and fitness in adolescence on cognition in adulthood and the role of insulin-like growth factor I
Author
Ferro, D.A.
Deijen, J.B.
Koppes, L.L.
van Mechelen, W.
Twisk, J.W.
Drent, M.L.
Publication year
2016
Abstract
Background: Physical activity and fitness in adolescence may improve cognition in adulthood by increasing insulin-like growth factor I (IGF-I). Methods: As part of the Amsterdam Growth and Health Longitudinal Study, following subjects from age 13 to 42 years, physical activity and fitness of 303 subjects were assessed annually between the ages 13 to 16. At mean age 36, physical activity, fitness and IGF-I were measured. At mean age 42, IGF-I and cognitive factors (ie, executive functioning and visual-spatial memory) were measured. The linear regression of physical activity and fitness in adolescence and IGF-I in adulthood on cognitive scores in adulthood was investigated. Results: A significant association was found in males between physical activity in adolescence and executive function in adulthood (Spatial Working Memory Between Errors: β = -.18, B = -.13, 95% CI = -.259 to -.010; Spatial Working Memory Strategy: β = -.20, B = -.08, 95% CI = -.147 to -.014). No association between physical activity or fitness in adolescence and cognitive function in adulthood was found in females, nor any intermediate role for IGF-I in either sex. Conclusions: The results suggest a stimulating effect of adolescent physical activity in males on executive functions in adulthood, emphasizing the importance of an active lifestyle among adolescent males. © 2016 Human Kinetics, Inc.
Subject
Life
WHC - Work, Health and Care
ELSS - Earth, Life and Social Sciences
Work and Employment
Workplace
Healthy Living
Cognitive aging
Executive function
IGF-I
Lifestyle
Memory
To reference this document use:
http://resolver.tudelft.nl/uuid:6afcc260-97d1-4930-a160-07a8f7c45e6b
DOI
https://doi.org/10.1123/jpah.2014-0594
TNO identifier
537433
ISSN
1543-3080
Source
Journal of Physical Activity and Health, 13 (4), 392-402
Document type
article