Print Email Facebook Twitter A case-cohort study on prostate cancer risk in relation to family history of prostate cancer Title A case-cohort study on prostate cancer risk in relation to family history of prostate cancer Author Schuurman, A.G. Zeegers, M.P.A. Goldbohm, R.A. van den Brandt, P.A. Centraal Instituut voor Voedingsonderzoek TNO Publication year 1999 Abstract We investigated the risk of prostate cancer in relation to a family history of prostate cancer in 58,279 men ages 55-69 years. We found 704 incident cases after 6.3 years of follow-up. Rate ratios and 95% confidence intervals for having an affected vs nonaffected father and brother were, respectively 1.44 (0.80-2.58) and 5.57 (1.61-19.26). We found no evidence for an increasing risk with an increasing percentage of affected family members. The associations we observed were stronger for cases diagnosed before age 70 compared with cases diagnosed after age 70 and for advanced compared with localized tumors. Subject NutritionAgeFamily historyProspective case-cohort studyProstate cancer riskAdultAgedCancer riskCohort analysisControlled studyFamily historyHumanMajor clinical studyMaleRostate cancerAgedCohort StudiesHumansMiddle AgedMultivariate AnalysisNetherlandsProstatic Neoplasms To reference this document use: http://resolver.tudelft.nl/uuid:4615e8d9-25cb-4f0e-8164-3b4ccab38600 TNO identifier 234973 ISSN 1044-3983 Source Epidemiology, 10 (2), 192-195 Document type article Files To receive the publication files, please send an e-mail request to TNO Library.