Title
Health-related quality of life for extremely low birth weight adolescents in Canada, Germany, and the Netherlands
Author
Verrips, E.
Vogels, T.
Saigal, S.
Wolke, D.
Meyer, R.
Hoult, L.
Verloove-Vanhorick, S.P.
TNO Kwaliteit van Leven
Publication year
2008
Abstract
OBJECTIVE.The goal was to compare health-related quality of life of 12- to 16-year-old adolescents born at an extremely low birth weight in regional cohorts from Ontario (Canada), Bavaria (Germany), and the Netherlands. METHODS. Patients were extremely low birth weight survivors from Canada, Germany, and the Netherlands. Health-related quality of life was assessed with Health Utilities Index 3. Missing data were substituted by proxy reports. Differences in mean Health Utilities Index 3 scores were tested by using analysis of variance. Differences in the numbers of children with affected attributes were tested by using logistic regression analyses. RESULTS.Survival rates were similar;response rates varied between 71% and 90%. Significant differences in health-related quality of life were found between the cohorts, with Dutch children scoring highest on Health Utilities Index 3 and German children scoring lowest, independent of birth weight, gestational age, and cerebral palsy. Differences in mean utility scores were mainly attributable to differences in the cognition health attribute. Most of the results were corroborated by logistic regression analyses. CONCLUSIONS. There were significant differences between the 3 cohorts in health- related quality of life, not related to differences in birth weight, gestational age, or cerebral palsy. Survival and response rates alone cannot explain these differences. Copyright © 2008 by the American Academy of Pediatrics.
Subject
Health
Cross-cultural
Extremely low birth weight
Health-related quality of life
Germany
Netherlands
Adolescent
Child
Follow-Up Studies
Germany
Health Status Indicators
Humans
Infant, Extremely Low Birth Weight
Infant, Newborn
Netherlands
Ontario
Prospective Studies
Quality of Life
Regression Analysis
Time Factors
To reference this document use:
http://resolver.tudelft.nl/uuid:0314ef32-6e9e-4f15-86da-80ae88c5ab97
DOI
https://doi.org/10.1542/peds.2007-1043
TNO identifier
240978
ISSN
0031-4005
Source
Pediatrics, 122 (3), 556-561
Document type
article